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Side Effects of Drugs Annual

Preface
Side Effects of Drugs: Annual (SEDA) is a yearly publication focused on existing, new and evolving side effects of drugs encountered by a broad range of healthcare pro-fessionals including physicians, pharmacists, nurse practitioners and advisors of poison control centres. This 37th edition of SEDA includes analyses of the side effects of drugs using both clinical trials and case-based principles which include encounters identified during bedside clinical practice over the 18 months since the previous edition. SEDA seeks to summarize the entire body of relevant medical literature into a single volume with dual goals of being comprehensive and of identifying emerging trends and themes in medicine as related to side effects and adverse drug effects (ADEs).
With a broad range of topics authored by practising clinicians and scientists, SEDA is a comprehensive and reliable reference to be used in clinical practice.
The majority of the chapters include relevant case studies that are not only peer-reviewed but also have a forward-looking, learning-based focus suitable for practitioners as well as students in training. The nationally and internationally known contributors believe this educational resource can be used to stimulate an active learning environment in a variety of settings. Each chapter in this volume has been reviewed by the editors, experienced clinical educators, actively practising clinicians and scientists to ensure the accuracy and timeliness of the information. The overall objective is to provide a framework for further understanding the intellectual approaches in analysing the implications of the case studies and their appropriateness when dispensing medications, as well as interpreting adverse drug reactions (ADRs), toxicity and outcomes resulting from medication errors.

Side Effects of Drugs Annual 40

Introduction :

Adverse drug events (ADEs), drug-induced toxicity and side effects are a significant concern. ADEs are known to pose a significant morbidity, mortality, and cost burden to society; however, there is a lack of strong evidence to determine their precise impact. The landmark Institute of Medicine (IOM) report To Err is Human implicated adverse drug events in 7000 annual deaths at an estimated cost of $2 billion. However, the US Department of Health and Human Services estimates 770 000 people are injured or die each year in hospitals from ADEs, which costs up to $5.6 million each year per hospital excluding the other accessory costs (e.g., hospital admissions due to ADEs, malpractice and litigation costs, or the costs of injuries).

Nationally, hospitals spend $1.56–5.6 billion each year to treat patients who suffer ADEs during hospitalization. A second landmark study suggests that approximately 28% of ADEs are preventable through optimization of medication safety and distribution systems, provision and dissemination of timely patient and medication information, and staffing assignments. Subsequent recent investigations suggest these numbers might be conservative estimates of the morbidity and mortality impact of ADEs.

ADVERSE EFFECTS


Advances in medical genomics have generated considerable beneficiaries for precision (personalized) medicine through the identification of genetic variants that alter drug response relative to drug efficacy or leading to either an exacerbation or minimization of adverse drug reactions (ADRs).

In the United States, ADRs occur in nearly 10% of patients taking prescription medications in the ambulatory setting and cause an estimated 100 000 deaths annually in hospitalized patients so The American Society of Health-System Pharmacists (ASHP) defines medication misadventures as unexpected, undesirable iatrogenic hazards or events where a medication was implicated.

These events can be broadly divided into two categories :

(i) medication errors
(ii) adverse drug events

(i) medication
errors (i.e., preventable events that may cause or contain inappropriate use), and
(ii) adverse drug events (i.e., any
injury, whether minor or significant, caused by a medication or lack thereof ).

About The Book

Side Effects of Drugs: Annual (SEDA) is a yearly publication focused on existing, new and evolving side effects of drugs encountered by a broad range of healthcare professionals including physicians, pharmacists, nurse practitioners and advisors of poison control centres. With a broad range of topics authored by practising clinicians and scientists, SEDA is a comprehensive and reliable reference to be used in clinical practice.

CONTENTS

Chapter 1 : Central Nervous System Stimulants and Drugs That Suppress Appetite
Chapter 2 : Antidepressants
Chapter 3 : Lithium
Chapter 4 : Drugs of Abuse
Chapter 5 : Hypnosedatives and Anxiolytics
Chapter 6 : Antipsychotic Drugs
Chapter 7 : Antiepileptics
Chapter 8 : Opioid Analgesics and Narcotic Antagonists
Chapter 9 : Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout
Chapter 10 : General Anaesthetics and Therapeutic Gases
Chapter 11 : Local Anesthetics
Chapter 12 : Neuromuscular Blocking Agents and Skeletal
Muscle Relaxants

****35 More Chapters are available in PDF

PDF INFO

Book’s Name Side Effects of Drugs Annual Volume 37
Author : PROF. M.N.G. DUKES, OSLO, NORWAY
Size Of PDF : 8 MB
Number of Pages : 651 Pages
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